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At present, people are concerned about BPA because BPA can migrate to human in various ways such as through food, beverages, environmental water and even baby bottles. Human exposure to BPA will have higher chance to get heart disease, diabetes, and reproduction defects. Newborns can have reduced birth weight and abnormal development of brain function. Besides, BPA can affect human’s endocrine function. The instability, insensitivity and low accuracy of instruments have made it difficult to screen BPA. Therefore, a new method should be developed to compensate for the inadequate of previous methods such as LLE and SPE.

Bisphenol A (BPA) is a chemical that is used to manufacture many daily products which include food container and hygiene products (Petre, 2016). BPA can present in dental application, water bottles, the inside lining of canned products, medical devices and many other daily products. There is a high possibility for human to take in BPA such as through their diet, air, water and dust (Micha?owicz, 2014). Moreover, BPA is best known for its application in producing polycarbonate plastics and epoxy resins which include those in beverage cans and baby bottles. The occasion of using epoxy resins is to avoid corrosion and stay inert (Rogers, n.d).

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